RIN1 Antikörper (AA 20-70)

Produktnummer ABIN6242616

Der Kaninchen Polyklonal Anti-RIN1-Antikörper wurde für WB validiert. Er ist geeignet, RIN1 in Proben von Human zu detektieren.

Kurzübersicht für RIN1 Antikörper (AA 20-70) (ABIN6242616)

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB46939

Produktdetails anti-RIN1 Antikörper

Bindungsspezifität: AA 20-70

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 20-70 amino acids from human.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu RIN1

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Andere Bezeichnung: RIN1

Hintergrund: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Molekulargewicht: 84099

UniProt: Q13671