Nicastrin Antikörper (AA 99-133)
Kurzübersicht für Nicastrin Antikörper (AA 99-133) (ABIN6242494)
Target
Alle Nicastrin (NCSTN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 99-133
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This NCSTN antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 99-133 amino acids from human NCSTN.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:2000. WB: 1:8000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- Nicastrin (NCSTN)
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Andere Bezeichnung
- NCSTN
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Hintergrund
- Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta- amyloid precursor protein). It probably represents a stabilizing cofactor required for the assembly of the gamma-secretase complex.
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Molekulargewicht
- 78411
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UniProt
- Q92542
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Pathways
- Notch Signalweg, Neurotrophin Signalübertragung
Target
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