NUP85 Antikörper (AA 163-195)

Produktnummer ABIN6242487

Der Kaninchen Polyklonal anti-NUP85 Antikörper wird verwendet zum Nachweis von NUP85 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für NUP85 Antikörper (AA 163-195) (ABIN6242487)

Target: NUP85 (Nucleoporin 85kDa (NUP85))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP85 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB55052

Produktdetails anti-NUP85 Antikörper

Bindungsspezifität: AA 163-195

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NUP85 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 163-195 amino acids from human NUP85.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu NUP85

Target: NUP85 (Nucleoporin 85kDa (NUP85))

Andere Bezeichnung: NUP85

Hintergrund: Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2- activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl- inositol 3-kinase-Rac-lammellipodium protrusion cascade.

Molekulargewicht: 75019

UniProt: Q9BW27