Myocardin Antikörper (C-Term)
Kurzübersicht für Myocardin Antikörper (C-Term) (ABIN6242477)
Target
Alle Myocardin (MYOCD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 743-777, C-Term
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Homologie
- H, Pig, Rat
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This Mouse Myocd antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 743-777 amino acids from the C-terminal region of Mouse Myocd.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:2000. WB: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- Myocardin (MYOCD)
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Andere Bezeichnung
- Myocd
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Hintergrund
- Smooth muscle cells (SM) and cardiac muscle cells- specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis). Isoform 1 mediates the cardiac transcription factor MEF2C-dependent transcription. Isoform 1 and isoform 3 are more active than isoform 2 and isoform 4 in stimulating cardiac muscle promoters.
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Molekulargewicht
- 101400
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UniProt
- Q8VIM5
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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