Importin 9 Antikörper (AA 1-388)

Produktnummer ABIN6242408

Dieser Maus Monoklonal Antikörper detektiert spezifisch Importin 9 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Importin 9 Antikörper (AA 1-388) (ABIN6242408)

Target: Importin 9 (IPO9)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Importin 9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1815CT202-22-8-37

Produktdetails anti-Importin 9 Antikörper

Bindungsspezifität: AA 1-388

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This RANBP9 antibody is generated from a mouse immunized with a recombinant protein between 1-388 amino acids from the human RANBP9.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:2000-1:4000. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu Importin 9

Target: Importin 9 (IPO9)

Andere Bezeichnung: RANBP9

Hintergrund: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but not affect estrogen-induced transactivation. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA (By similarity).

Molekulargewicht: 77847

UniProt: Q96S59

Pathways: Protein targeting to Nucleus