FOXN4 Antikörper (C-Term)

Produktnummer ABIN6242346

Der Kaninchen Polyklonal Anti-FOXN4-Antikörper wurde für WB validiert. Er ist geeignet, FOXN4 in Proben von Human zu detektieren.

Kurzübersicht für FOXN4 Antikörper (C-Term) (ABIN6242346)

Target: FOXN4 (Forkhead Box N4 (FOXN4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXN4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB52411

Produktdetails anti-FOXN4 Antikörper

Bindungsspezifität: AA 436-470, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FOXN4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 436-470 amino acids from the C-terminal region of human FOXN4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu FOXN4

Target: FOXN4 (Forkhead Box N4 (FOXN4))

Andere Bezeichnung: FOXN4

Hintergrund: Transcription factor essential for neural and some non- neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4- NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).

Molekulargewicht: 55215

UniProt: Q96NZ1