This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This EWSR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 328-362 amino acids from the Central region of human EWSR1.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Target
EWSR1
(Ewing Sarcoma Breakpoint Region 1 (EWSR1))
Andere Bezeichnung
EWSR1
Hintergrund
Might normally function as a transcriptionnal repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.