This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen
This CBX8 antibody is generated from a mouse immunized with a KLH conjugated synthetic peptide between amino acids from the C-terminal region of human CBX8.
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Target
CBX8
(Chromobox Homolog 8 (CBX8))
Andere Bezeichnung
CBX8
Hintergrund
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.