Klotho beta Antikörper (AA 1-29)
Kurzübersicht für Klotho beta Antikörper (AA 1-29) (ABIN6242210)
Target
Alle Klotho beta (KLB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 1-29
-
Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogen
- This KLB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from human KLB.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- WB: 1:2000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Haltbarkeit
- 6 months
-
-
- Klotho beta (KLB)
-
Andere Bezeichnung
- KLB
-
Hintergrund
- Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21 (By similarity).
-
Molekulargewicht
- 119808
-
UniProt
- Q86Z14
-
Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Growth Factor Binding
Target
-