RBBP5
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000. ICC: 1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Lagerung
4 °C,-20 °C
Target
RBBP5
(Retinoblastoma Binding Protein 5 (RBBP5))
Andere Bezeichnung
RBBP5
Hintergrund
In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid (By similarity). As part of the MLL1/MLL complex, involved in mono-, di- and trimethylation at 'Lys-4' of histone H3. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation.