Der Kaninchen Polyklonal anti-IGF2R Antikörper wird verwendet zum Nachweis von IGF2R in Proben von Human, Maus und Ratte. Er wurde validiert für WB und IHC.
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.