Der Kaninchen Polyklonal Anti-IGF2R-Antikörper wurde für WB und IHC validiert. Er ist geeignet, IGF2R in Proben von Human, Maus und Ratte zu detektieren.
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.