SRSF1 Antikörper (pSer1)

Produktnummer ABIN3022320

This anti-SRSF1 antibody (ABIN3022320) is a Rabbit Polyclonal antibody detecting SRSF1 in WB, IHC. Suitable for Human, Mouse, Rat.

Kurzübersicht für SRSF1 Antikörper (pSer1) (ABIN3022320)

Target: SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRSF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SRSF1 Antikörper

Bindungsspezifität: pSer1

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human SFR pSer1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C/-80 °C

Details zu SRSF1

Target: SRSF1 (serine/arginine-Rich Splicing Factor 1 (SRSF1))

Andere Bezeichnung: SFRS1

Hintergrund: SF2/ASF is a member of the Ser-Arg-rich (SR) protein family of highly conserved nuclear phosphoproteins involved in pre-mRNA splicing. Besides its role in nuclear pre-mRNA splicing, SF2/ASF has been shown to shuttle between the nucleus and cytoplasm, suggesting additional roles in mRNA transport and cytoplasmic events. SF2/ASF associates with translating ribosomes and stimulates translation. It also activates translation initiation by suppressing the activity of 4E-BP1, which is mediated by SF2/ASF association with mTOR and the phosphatase PP2A. More recent studies have demonstrated a role for SF2/ASF in microRNA processing.
Synonyms: ASF, MGC5228, SF2, SF2p33, SRp30a

Gen-ID: 6426

UniProt: Q07955

Pathways: Ribonucleoprotein Complex Subunit Organization