FTL Antikörper (AA 38-165) (Biotin)
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- Target Alle FTL Antikörper anzeigen
- FTL (Ferritin, Light Polypeptide (FTL))
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Bindungsspezifität
- AA 38-165
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FTL Antikörper ist konjugiert mit Biotin
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Verwendungszweck
- Mouse Monoclonal anti-Ferritin, Light chain (FTL/1388), Biotin Conjugate
- Produktmerkmale
- Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human FTL protein fragment (aa 38-165) (exact sequence is proprietary)
- Klon
- FTL-1388
- Isotyp
- IgG2a
- Top Product
- Discover our top product FTL Primärantikörper
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- Applikationshinweise
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Immunohistology (formalin) 0.1-0.2 μg/mL
- Flow cytometry 0.1-0.2 μg/million cells Immunofluorescence 0.1-0.2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Optimal dilution for a specific application should be determined by user
- Kommentare
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HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- FTL (Ferritin, Light Polypeptide (FTL))
- Andere Bezeichnung
- Ferritin, Light chain (FTL Produkte)
- Synonyme
- NBIA3 antikoerper, apoferritin antikoerper, ferritin antikoerper, fhc antikoerper, fth antikoerper, fth1 antikoerper, fthl6 antikoerper, ftn-2 antikoerper, pig15 antikoerper, plif antikoerper, FT antikoerper, Ftl antikoerper, Ftl-1 antikoerper, L-ferritin antikoerper, FTL antikoerper, Ftl1 antikoerper, FTL2 antikoerper, FTD antikoerper, ferritin light chain antikoerper, ferritin, heavy polypeptide 1 L homeolog antikoerper, ferritin light polypeptide 1 antikoerper, ferritin, light polypeptide antikoerper, ferritin light-chain antikoerper, ferritin light chain 1 antikoerper, FTL antikoerper, fth1.L antikoerper, Ftl1 antikoerper, CpipJ_CPIJ004069 antikoerper, Ftl antikoerper
- Hintergrund
- Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3
- Molekulargewicht
- 19-25 kDa
- Gen-ID
- 2512, 433670
- UniProt
- P02792
- Pathways
- Transition Metal Ion Homeostasis
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