Rekombinanter CA 19-9 Antikörper (CF®647)

Produktnummer ABIN6190532

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch CA 19-9 in IHC, FACS und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter CA 19-9 Antikörper (CF®647) (ABIN6190532)

Target: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CA 19-9 Antikörper ist konjugiert mit CF®647

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: CA19-9-1390R

Produktdetails anti-CA 19-9 Antikörper (CF®647)

Verwendungszweck: Recombinant Rabbit Monoclonal anti-CA19-9/Sialyl-Lewisa (CA19.9/1390R), CF647 Conjugate

Produktmerkmale: CA19-9, a carbohydrate epitope expressed on a high MW (>400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Purified human CA19-9 protein

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: Immunofluorescence 0.5-1 μg/mL Immunohistology (formalin) 5-10 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer  pH 6.0for 10-20 min followed by cooling at RT for 20 min
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

Stomach or Colon Carcinoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu CA 19-9

Target: CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

Andere Bezeichnung: CA19-9/Sialyl-Lewisa

Hintergrund: CA19.9, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl Lewis a

Molekulargewicht: >400 kDa