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Testosterone Antikörper (CF®594)

ELISA, IHC, Coat, ISt Wirt: Maus Monoclonal 4E1G2 CF®594
Produktnummer ABIN6189864
  • Target Alle Testosterone Antikörper anzeigen
    Testosterone
    Reaktivität
    Bitte anfragen
    Wirt
    • 28
    • 10
    • 3
    Maus
    Klonalität
    • 29
    • 12
    Monoklonal
    Konjugat
    • 26
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Testosterone Antikörper ist konjugiert mit CF®594
    Applikation
    • 31
    • 16
    • 11
    • 9
    • 9
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Coating (Coat), Immunostaining (ISt)
    Verwendungszweck
    Mouse Monoclonal anti-Testosterone (4E1G2), CF594 Conjugate
    Produktmerkmale
    This MAb is highly specific to testosterone. Its affinity constant for testosterone is ~1010 M-1. In competitive binding immunoassay, it reacts with testosterone 100 % , 11-beta-hydroxy testosterone 3.3 %, 17-alpha-methyl testosterone <0.1 %, 5-alpha DHT 0.8 %, estradiol <0.1 % and progesterone <0.1 %. Testosterone, a steroid hormone from the androgen group, is derived from cholesterol. Testosterone is primarily secreted in the testes, but the ovaries and adrenal glands also produce smaller amounts. It is the principal male sex hormone and is responsible for the maturation of sex organs and the development of male secondary sex characteristics. The hormone is also involved in the growth of muscle mass and increases bone density and maturation. It functions by activating the androgen receptor and converting to estradiol and activation of estrogen receptors. Testosterone has been employed therapeutically to treat many conditions including infertility, lack of libido, osteoporosis, height growth and bone marrow stimulation. Anti-testosterone antibody may also prove useful in identification of testicular tumors arising from interstitial cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Immunogen
    Testosterone 3 CMO conjugated to BSA
    Klon
    4E1G2
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product Testosterone Primärantikörper
  • Applikationshinweise
    Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM citrate buffer  pH 6.0 for 10-20 min followed by cooling at RT for 20 min
    • Immunohistology formalin-paraffin 0.25-0.5 μg/mL
    • ELISA For coating, order Ab without BSA
    • Optimal dilution for a specific application should be determined by user
    Kommentare

    Interstitial or Leydid cells in testis.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    100 μg/mL
    Buffer
    PBS/0.1 % BSA/0.05 % azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from light
  • Target
    Testosterone
    Abstract
    Testosterone Produkte
    Substanzklasse
    Hormone
    Hintergrund
    17i²-Hydroxy-3-oxo-4-androstene, 17i²-Hydroxy-4-androsten-3-one, 4-Androsten-17i²-ol-3-one, trans-Testosterone
    Molekulargewicht
    288.42Da
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