CD81 Antikörper (CF®640R)
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- Target Alle CD81 Antikörper anzeigen
- CD81
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD81 Antikörper ist konjugiert mit CF®640R
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Applikation
- Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Functional Studies (Func)
- Verwendungszweck
- Mouse Monoclonal anti-CD81 / TAPA-1 (1.3.3.22), CF640R Conjugate
- Produktmerkmale
- This antibody This antibody recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- B-Cell line derived from a Burkitt lymphoma
- Klon
- 1-3-3-22
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD81 Primärantikörper
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- Applikationshinweise
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For functional studies, order Ab without azide
- Immunohistology (formalin) 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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Ramos, Daudi, Raji, U266, HUT-78, HUT-102, Jurkat, HL-60, KG1a, A293, A431, MG63, and human lymphocytes. Tonsil or Liver.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- CD81
- Andere Bezeichnung
- CD81 / TAPA-1 (CD81 Produkte)
- Synonyme
- Tapa-1 antikoerper, Tapa1 antikoerper, Tspan28 antikoerper, CVID6 antikoerper, S5.7 antikoerper, TAPA1 antikoerper, TSPAN28 antikoerper, CD81 molecule antikoerper, CD81 molecule b antikoerper, CD81 antigen antikoerper, Cd81 molecule antikoerper, CD81 antikoerper, cd81b antikoerper, Cd81 antikoerper
- Hintergrund
- CD81, Target of the antiproliferative antibody 1 (TAPA-1), Tetraspanin-28, Tspan-28
- Molekulargewicht
- 26 kDa
- Gen-ID
- 975, 54457
- UniProt
- P60033
- Pathways
- Inositol Metabolic Process, Hepatitis C
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