HIV-1 p24 Antikörper (CF405M)

Produktnummer ABIN6186498

Dieses Maus Monoklonal-Antikörper erkennt spezifisch HIV-1 p24 in ELISA, IF, ICC und Coat. Er zeigt eine Reaktivität gegenüber Human Immunodeficiency Virus (HIV).

Kurzübersicht für HIV-1 p24 Antikörper (CF405M) (ABIN6186498)

Target: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Reaktivität: Human Immunodeficiency Virus (HIV)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HIV-1 p24 Antikörper ist konjugiert mit CF405M

Applikation: ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Coating (Coat)

Klon: P24-661

Produktdetails anti-HIV-1 p24 Antikörper (CF405M)

Verwendungszweck: Mouse Monoclonal anti-HIV p24 (p24/661), CF405M Conjugate

Produktmerkmale: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4 T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant HIV-1 Gag p24 protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Immunocytochemistry Acetone or paraformaldehyde fixed 0.5-1 μg/mL

• Immunofluorescence 0.5-1 μg/mL
• ELISA For coating, order Ab without BSA
• Optimal dilution for a specific application should be determined by user

Kommentare:

HIV-1 infected cells or tissues.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu HIV-1 p24

Target: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Andere Bezeichnung: HIV p24

Substanzklasse: Viral Protein

Hintergrund: Capsid protein p24, Human immunodeficiency virus type 1 p24, HIV1gp1, HIV-1 Gag p24

Molekulargewicht: 24 kDa (mature), 55 kDa & 41 kDa (precursors)

Gen-ID: 155348