HCG beta Antikörper (CF®647)

Produktnummer ABIN6180766

Der Maus Monoklonal Anti-HCG beta-Antikörper wurde für IHC (fro) validiert. Er ist geeignet, HCG beta in Proben von Human zu detektieren.

Kurzübersicht für HCG beta Antikörper (CF®647) (ABIN6180766)

Target: HCG beta

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HCG beta Antikörper ist konjugiert mit CF®647

Applikation: Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: HCGb-211

Produktdetails anti-HCG beta Antikörper (CF®647)

Verwendungszweck: Mouse Monoclonal anti-HCG beta (HCGb/211), CF647 Conjugate

Produktmerkmale: This MAb reacts with a protein of 22 kDa, identified as β sub-unit of HCG. It does not cross react with the α sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? and ? subunits. The ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90 % and 60 % of cases respectively. 20 % of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Purified human HCG-beta

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunohistology (frozen) 0.5-1 μg/mL

Kommentare:

Placenta

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu HCG beta

Target: HCG beta

Hintergrund: CG-beta, CGB3, CGB5, CGB7, CGB8, Choriogonadotropin Subunit beta, hCGB

Molekulargewicht: 22 kDa

Gen-ID: 1082, 172944

UniProt: P01233