DC-SIGN/CD209 Antikörper (CF®405S)

Produktnummer ABIN6179466

Dieses Maus Monoklonal-Antikörper erkennt spezifisch DC-SIGN/CD209 in FACS, IHC, IF und ISt. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DC-SIGN/CD209 Antikörper (CF®405S) (ABIN6179466)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist konjugiert mit CF®405S

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunostaining (ISt)

Klon: C209-1781

Produktdetails anti-DC-SIGN/CD209 Antikörper (CF®405S)

Verwendungszweck: Mouse Monoclonal anti-CD209 / DC-SIGN (C209/1781), CF405S Conjugate

Produktmerkmale: DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human CD209 protein fragment

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA Buffer  pH 9.0for 10-20 min followed by cooling at RT for 20 min

• Immunohistology (formalin) 0.5 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

THP-1 or HeLa Cells. Small Intestine, Uterus or Lymph Node.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: CD209 / DC-SIGN

Hintergrund: CD209, CDSIGN, CIRE, CLEC4L, DC-SIGN, DC-SIGN1, DCSIGN, Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1, HIV GP120 Binding Protein, SIGN-R1, SIGNR5

Molekulargewicht: 45 kDa

Gen-ID: 30835, 278694

UniProt: Q9NNX6