EPX Antikörper

Produktnummer ABIN6173725

Der Maus Monoklonal Anti-EPX-Antikörper wurde für FACS und IF validiert. Er ist geeignet, EPX in Proben von Human zu detektieren.

Kurzübersicht für EPX Antikörper (ABIN6173725)

Target: EPX (Eosinophil Peroxidase (EPX))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPX Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: AHE-1

Produktdetails anti-EPX Antikörper

Verwendungszweck: Mouse Monoclonal anti-Eosinophil Peroxidase (AHE-1), Purified, with BSA

Produktmerkmale: Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Aufreinigung: Purified

Immunogen: Human eosinophils from a patient with hypereosinophilic syndrome

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Immunofluorescence 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

MCF-7 cells. Tonsil

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 200 μg/mL

Buffer: PBS/0.05 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu EPX

Target: EPX (Eosinophil Peroxidase (EPX))

Andere Bezeichnung: Eosinophil Peroxidase

Hintergrund: Eosinophil peroxidase heavy chain, EPER, EPO, EPP, EPX, EPX PEN, PERE

Molekulargewicht: 70 kDa (55 kDa-Heavy Chain, 15 kDa-Light Chain)

Gen-ID: 8288, 279259

UniProt: P11678