KRT14 Antikörper (C-Term) (CF®647)
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- Target Alle KRT14 Antikörper anzeigen
- KRT14 (Keratin 14 (KRT14))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser KRT14 Antikörper ist konjugiert mit CF®647
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Verwendungszweck
- Mouse Monoclonal anti-Cytokeratin 14 (LL002), CF647 Conjugate
- Produktmerkmale
- Cytokeratin 14 (CK14) belongs to the type I (or A or acidic) subfamily of low molecular weight keratins and exists in combination with keratin 5 (type II or B or basic). CK14 is found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is useful in differentiating squamous cell carcinomas from poorly differentiated epithelial tumors. Anti-CK14 is one of the specific basal markers for distinguishing between basal and non-basal subtypes of breast carcinomas. Anti-CK14 is also a good marker for differentiation of intraductal from invasive salivary duct carcinoma by the positive staining of basal cells surrounding the in-situ neoplasm as well as for differentiation of benign prostate from prostate carcinoma. Furthermore, this antibody has been useful in separating oncocytic tumors of the kidney from its renal mimics, and in identifying metaplastic carcinomas of the breast. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- A synthetic peptide of 15 amino acid from the C-terminus of human keratin 14.
- Klon
- LL002
- Isotyp
- IgG3
- Top Product
- Discover our top product KRT14 Primärantikörper
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- Applikationshinweise
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Immunohistology formalin-fixed 0.5-1.0 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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A431 cells. Skin or Squamous cell carcinoma
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- KRT14 (Keratin 14 (KRT14))
- Andere Bezeichnung
- Cytokeratin 14 (KRT14 Produkte)
- Synonyme
- CK14 antikoerper, EBS3 antikoerper, EBS4 antikoerper, K14 antikoerper, NFJ antikoerper, AI626930 antikoerper, Krt-1.14 antikoerper, Krt1-14 antikoerper, Ka14 antikoerper, ouro2 antikoerper, keratin 14 antikoerper, keratin 14, type I L homeolog antikoerper, KRT14 antikoerper, Krt14 antikoerper, krt14.L antikoerper
- Hintergrund
- CK-14, Dowling Meara, ebs3, ebs4, Epidermolysis Bullosa Simplex, k14, Keratin 14, Keratin Type I Cytoskeletal 14, Koebner, krt14, NFJ
- Molekulargewicht
- ~50 kDa
- Gen-ID
- 3861, 6545380
- UniProt
- P02533
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