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Uroplakin 3A Antikörper (AA 260-279) (CF®488A)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Uroplakin 3A in WB, IF und FACS. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6168105

Kurzübersicht für Uroplakin 3A Antikörper (AA 260-279) (CF®488A) (ABIN6168105)

Target

Alle Uroplakin 3A (UPK3A) Antikörper anzeigen
Uroplakin 3A (UPK3A)

Reaktivität

  • 48
  • 6
  • 3
  • 3
  • 2
  • 1
Human

Wirt

  • 32
  • 21
Kaninchen

Klonalität

  • 31
  • 22
Polyklonal

Konjugat

  • 39
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Uroplakin 3A Antikörper ist konjugiert mit CF®488A

Applikation

  • 42
  • 27
  • 22
  • 19
  • 11
  • 11
  • 6
  • 2
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon

PAb
  • Bindungsspezifität

    • 13
    • 10
    • 3
    • 2
    • 1
    • 1
    AA 260-279

    Verwendungszweck

    Polyclonal-anti-UPK3A (Uroplakin-3A) (Rabbit-PAb), CF488A Conjugate

    Produktmerkmale

    Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Immunogen

    A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

    Isotyp

    IgG
  • Applikationshinweise

    Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user

    Kommentare

    HEK293 cells or bladder carcinoma

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    100 μg/mL

    Buffer

    PBS/0.1 % BSA/0.05 % azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from light
  • Target

    Uroplakin 3A (UPK3A)

    Andere Bezeichnung

    -UPK3A (Uroplakin-3A) (-)

    Hintergrund

    UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A

    Molekulargewicht

    ~30 kDa

    Gen-ID

    7380, 632787

    UniProt

    O75631
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