CD52 Antikörper (APC)

Produktnummer ABIN616802

Der Maus Monoklonal Anti-CD52 Antikörper wurde für FACS validiert. Er ist geeignet, CD52 in Proben von Human zu detektieren.

Kurzübersicht für CD52 Antikörper (APC) (ABIN616802)

Target: CD52

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD52 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: HI186

Produktdetails anti-CD52 Antikörper (APC)

Spezifität: This antibody reacts with Human CD52 (CAMPATH-1), a 21-28 kDa glycoprotein containing a large N-linked carbohydrate moiety, mature CD52 Molecule is actually much smaller (approx. 8-9 kDa). CD52 is expressed at high levels on lymphocytes, monocytes/macrophages and in male reproductive tract.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Size-Exclusion Chromatography

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade protease free BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu CD52

Target: CD52

Andere Bezeichnung: CD52 / CAMPATH-1

Hintergrund: CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.Synonyms: CDw52, Cambridge pathology 1 antigen, Epididymal secretory protein E5, HE5

Gen-ID: 1043