CD7 Antikörper (PE)

Produktnummer ABIN616789

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD7 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD7 Antikörper (PE) (ABIN616789)

Target: CD7

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD7 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: MEM-186

Produktdetails anti-CD7 Antikörper (PE)

Spezifität: This antibody reacts with CD7, a 40 kDa type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu CD7

Target: CD7

Andere Bezeichnung: CD7

Hintergrund: CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41

Gen-ID: 924

Pathways: Cell-Cell Junction Organization