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CD7 Antikörper (APC)

CD7 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-186 APC

Produktnummer ABIN616787

Datenblatt (PDF)

Target Alle CD7 Antikörper anzeigen

CD7
Reaktivität
186

25

10

10

7
Human
Wirt
101

85

1

1
Maus
Passende Sekundärantikörper
Klonalität
104

83

1
Monoklonal
Konjugat
66

19

15

14

10

8

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD7 Antikörper ist konjugiert mit APC
Applikation
109

67

52

30

25

16

12

12

7

5

3

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

This antibody reacts with CD7, a 40 kDa type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.

Kreuzreaktivität (Details)

Species reactivity (tested):Human

Klon

MEM-186

Isotyp

IgG1

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anti-CD7 (CD7) antibody
CD7 Reaktivität: Human IHC Wirt: Kaninchen Monoclonal MSVA-007R unconjugated Recombinant Antibody

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target

CD7

Andere Bezeichnung

CD7 (CD7 Produkte)

Synonyme

GP40 antikoerper, LEU-9 antikoerper, TP41 antikoerper, Tp40 antikoerper, CD7 molecule antikoerper, CD7 antigen antikoerper, Cd7 molecule antikoerper, CD7 antikoerper, Cd7 antikoerper

Hintergrund

CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41

Gen-ID

924

Pathways

Cell-Cell Junction Organization