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MVP Antikörper (CF®488A)

MVP Reaktivität: Human FACS, IF Wirt: Maus Monoclonal 1014 CF®488A
Produktnummer ABIN6165331
  • Target Alle MVP Antikörper anzeigen
    MVP (Major Vault Protein (MVP))
    Reaktivität
    • 90
    • 28
    • 26
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 57
    • 35
    • 1
    Maus
    Klonalität
    • 47
    • 46
    Monoklonal
    Konjugat
    • 55
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser MVP Antikörper ist konjugiert mit CF®488A
    Applikation
    • 49
    • 34
    • 29
    • 27
    • 24
    • 16
    • 9
    • 8
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Verwendungszweck
    Mouse Monoclonal anti-Major Vault Protein (MVP) (1014), CF488A Conjugate
    Produktmerkmale
    This antibody recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70 % of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Immunogen
    Proteins precipitated from human breast cancer MCF-7 cells
    Klon
    1014
    Isotyp
    IgG1 kappa
    Top Product
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  • Applikationshinweise
    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    Kommentare

    MCF-7/HeLa, breast tumors

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    100 μg/mL
    Buffer
    PBS/0.1 % BSA/0.05 % azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from light
  • Target
    MVP (Major Vault Protein (MVP))
    Abstract
    MVP Produkte
    Synonyme
    LRP antikoerper, VAULT1 antikoerper, 2310009M24Rik antikoerper, cb771 antikoerper, wu:fb52b05 antikoerper, wu:fc02g01 antikoerper, mvp antikoerper, MGC145641 antikoerper, Tb05.45E22.810 antikoerper, major vault protein antikoerper, major vault protein L homeolog antikoerper, putative major vault protein antikoerper, MVP antikoerper, Mvp antikoerper, mvp antikoerper, mvp.L antikoerper, Tc00.1047053510353.10 antikoerper, Tb927.5.4460 antikoerper, Tb10.70.0520 antikoerper, Tb10.70.5840 antikoerper, LMJF_05_0060 antikoerper
    Hintergrund
    Lung resistance-related protein (LRP), Major Vault Protein, MVP, VAULT1
    Molekulargewicht
    104-110 kDa
    Gen-ID
    9961, 632177
    UniProt
    Q14764
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