JUP Antikörper (CF®647)

Produktnummer ABIN6164899

Der Maus Monoklonal Anti-JUP-Antikörper wurde für WB, IF und FACS validiert. Er ist geeignet, JUP in Proben von Human, Maus, Ratte, Huhn, Rind (Kuh), Hund und Cat zu detektieren.

Kurzübersicht für JUP Antikörper (CF®647) (ABIN6164899)

Target: JUP (Junction Plakoglobin (JUP))

Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser JUP Antikörper ist konjugiert mit CF®647

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: 15F11

Produktdetails anti-JUP Antikörper (CF®647)

Verwendungszweck: Mouse Monoclonal anti-Catenin, gamma (15F11), CF647 Conjugate

Produktmerkmale: This antibody recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (?, ?, ? and ?) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. ? T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. ? T-catenin binds to ? E-catenin as well as to ?-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for ?-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: full length chicken Catenin gamma protein|Recombinant

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow Cytometry 0.5-1 μg/million cells/0.1 mL

• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

A431, T47D or MCF-7 cells. Skin

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu JUP

Target: JUP (Junction Plakoglobin (JUP))

Andere Bezeichnung: Catenin, gamma

Hintergrund: ARVD12, Catenin (cadherin-associated protein), gamma 80  kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB

Molekulargewicht: 80-87 kDa

Gen-ID: 3728, 514174

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location