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Granulocyte Marker Antikörper (CF®647)

Reaktivität: Human FACS, IF, IHC (f), IHC (p), ISt Wirt: Maus Monoclonal BM-1 CF®647
Produktnummer ABIN6163531
  • Target
    Granulocyte Marker
    Reaktivität
    • 12
    • 4
    Human
    Wirt
    • 12
    Maus
    Klonalität
    • 12
    Monoklonal
    Konjugat
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    CF®647
    Applikation
    • 11
    • 11
    • 9
    • 8
    • 8
    • 3
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunostaining (ISt)
    Verwendungszweck
    Mouse Monoclonal anti-Granulocyte Marker (BM-1), CF647 Conjugate
    Produktmerkmale
    This antibody recognizes a 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid specific antigen. It reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. Markers of myeloid cells are useful in the identification of different levels of cellular differentiation. This MAb reacts with early precursor and mature forms of human myeloid cells. It is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of this antigen is not clear, although it has been proposed that it may play a role in the differentiation of myeloid cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Immunogen
    Human peripheral blood mononuclear cells
    Klon
    BM-1
    Isotyp
    IgG1
  • Applikationshinweise
    Immunohistology formalin-fixed 0.5-1 μg/mL
    • No special pretreatment is required for staining of formalin/paraffin tissues
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user
    Kommentare

    HL60 cells. Bone marrow, lymph node or tonsil

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    100 μg/mL
    Buffer
    PBS/0.1 % BSA/0.05 % azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from light
  • Target
    Granulocyte Marker
    Hintergrund
    Myeloid specific protein, p183 DNA-binding cytoplasmic protein
    Molekulargewicht
    183 kDa
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