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MHC, Class I Antikörper

Dieses Anti-MHC, Class I-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MHC, Class I in FACS und IF. Geeignet für Maus, Human und Non-Human Primate.
Produktnummer ABIN6155390

Kurzübersicht für MHC, Class I Antikörper (ABIN6155390)

Target

Alle MHC, Class I Antikörper anzeigen
MHC, Class I

Reaktivität

  • 71
  • 45
  • 13
  • 9
  • 7
  • 6
  • 5
  • 5
  • 5
  • 5
  • 4
  • 1
Maus, Human, Non-Human Primate

Wirt

  • 65
  • 47
  • 7
  • 1
Maus

Klonalität

  • 81
  • 36
  • 3
Monoklonal

Konjugat

  • 37
  • 15
  • 12
  • 9
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MHC, Class I Antikörper ist unkonjugiert

Applikation

  • 75
  • 55
  • 34
  • 25
  • 21
  • 14
  • 14
  • 13
  • 13
  • 11
  • 7
  • 5
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)

Klon

246-B8-E7
  • Verwendungszweck

    Mouse Monoclonal anti-MHC-I (246-B8.E7), Purified, BSA-free

    Produktmerkmale

    This antibody recognizes a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    Aufreinigung

    Purified

    Immunogen

    Human peripheral blood leukocytes

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    Kommentare

    THP-1 and Jurkat cells. Tonsil or lymph node.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS (no BSA, no azide)

    Konservierungsmittel

    Azide free
  • Target

    MHC, Class I

    Andere Bezeichnung

    MHC-I

    Hintergrund

    HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A B C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC

    Molekulargewicht

    ~41 kDa

    Gen-ID

    3105, 181244, 654404

    UniProt

    P01889, P30443, P30499
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