PDE4B Antikörper (C-Term)

Produktnummer ABIN615425

Der Ziege Polyklonal anti-PDE4B Antikörper wird verwendet zum Nachweis von PDE4B in Proben von Human. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für PDE4B Antikörper (C-Term) (ABIN615425)

Target: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PDE4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PDE4B Antikörper

Bindungsspezifität: C-Term

Sequenz: C-DIDIATEDKS PVDT

Spezifität: This antibody detects PDE4B (C-term) and is expected to recognize all reported isoforms.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from C-terminus of Human PDE4B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH ~7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PDE4B

Target: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Andere Bezeichnung: PDE4B

Hintergrund: Phosphodiesterase 4B, a cAMP-specific phosphodiesterase, regulates pro-inflammatory and immune cells, and may function in learning, leukemia, memory (or other brain functions), and penile erectile dysfunction. PDE4B activity is inhibited by rolipram. At least three PDE4B isoforms, produced by alternative splicing, have been reported.Synonyms: 5'-cyclic phosphodiesterase 4B, DPDE4, EC=3.1.4.17, PDE32, PDE4B, cAMP-specific 3'

Gen-ID: 5142

NCBI Accession: NP_001032416

UniProt: Q07343

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction