PDE4B Antikörper (C-Term)

Produktnummer ABIN615425

Produktdetails anti-PDE4B Antikörper

Target: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser PDE4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequenz: C-DIDIATEDKS PVDT

Spezifität: This antibody detects PDE4B (C-term) and is expected to recognize all reported isoforms.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from C-terminus of Human PDE4B

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH ~7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PDE4B

Target: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Andere Bezeichnung: PDE4B (PDE4B Produkte)

Synonyme: dpde4 antikoerper, pde4b5 antikoerper, pdeivb antikoerper, Dpde4 antikoerper, R74983 antikoerper, dunce antikoerper, PDE4/IVb antikoerper, Pde4B1 antikoerper, Pde4B2 antikoerper, Pde4B3 antikoerper, Pde4B4 antikoerper, DPDE4 antikoerper, PDE4B5 antikoerper, PDEIVB antikoerper, phosphodiesterase 4B antikoerper, phosphodiesterase 4B, cAMP specific antikoerper, phosphodiesterase 4B S homeolog antikoerper, pde4b antikoerper, PDE4B antikoerper, Pde4b antikoerper, pde4b.S antikoerper

Hintergrund: Phosphodiesterase 4B, a cAMP-specific phosphodiesterase, regulates pro-inflammatory and immune cells, and may function in learning, leukemia, memory (or other brain functions), and penile erectile dysfunction. PDE4B activity is inhibited by rolipram. At least three PDE4B isoforms, produced by alternative splicing, have been reported.Synonyms: 5'-cyclic phosphodiesterase 4B, DPDE4, EC=3.1.4.17, PDE32, PDE4B, cAMP-specific 3'

Gen-ID: 5142

NCBI Accession: NP_001032416

UniProt: Q07343

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction