Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

HLA-DP beta Antikörper (CF®405S)

HLA-DP beta Reaktivität: Human FACS, IF, IHC (f) Wirt: Maus Monoclonal Bra-14 CF®405S
Produktnummer ABIN6153339
  • Target Alle HLA-DP beta Produkte
    HLA-DP beta (MHC Class II HLA-DP beta (HLA-DP beta))
    Reaktivität
    Human
    Wirt
    • 17
    Maus
    Klonalität
    • 17
    Monoklonal
    Konjugat
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser HLA-DP beta Antikörper ist konjugiert mit CF®405S
    Applikation
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Verwendungszweck
    Mouse Monoclonal anti-MHC-II (HLA-DP beta chain) (Bra-14), CF405S Conjugate
    Produktmerkmale
    This antibody recognizes a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DR and DP. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Immunogen
    Human REH cells
    Klon
    Bra-14
    Isotyp
    IgG3 kappa
  • Applikationshinweise
    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    Kommentare

    Raji cells. Tonsil or lymph node

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    100 μg/mL
    Buffer
    PBS/0.1 % BSA/0.05 % azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Protect from light
  • Target
    HLA-DP beta (MHC Class II HLA-DP beta (HLA-DP beta))
    Andere Bezeichnung
    MHC-II (HLA-DP) (beta chain) (HLA-DP beta Produkte)
    Molekulargewicht
    36 kDa (? chain) and 27 kDa (? chain)
    Gen-ID
    3115, 3122
Sie sind hier:
Kundenservice