LGALS1/Galectin 1 Antikörper (AA 12-108) (CF®594)
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- Target Alle LGALS1/Galectin 1 (LGALS1) Antikörper anzeigen
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
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Bindungsspezifität
- AA 12-108
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LGALS1/Galectin 1 Antikörper ist konjugiert mit CF®594
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
- Verwendungszweck
- Mouse Monoclonal anti-Galectin-1 / Human Placental Lactogen (GAL1/1831), CF594 Conjugate
- Produktmerkmale
- Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human Galectin-1 protein fragment (aa12-108) (exact sequence is proprietary)
- Klon
- GAL1-1831
- Isotyp
- IgG Mix lambda
- Top Product
- Discover our top product LGALS1 Primärantikörper
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- Applikationshinweise
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Flow cytometry 0.5-1 μg/million cells in 0.1 mL
- Immunohistology (formalin) 0.5-1 μg/mL
- ELISA 2-4 μg/mL for coating (order Ab without BSA)
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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HeLa, K562 or 293 cells. Prostate, Kidney, Placenta, Stomach, Skin, Spleen, Brain or Heart.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
- Andere Bezeichnung
- Galectin-1 / Placental Lactogen (LGALS1 Produkte)
- Synonyme
- GAL1 antikoerper, GBP antikoerper, Galectin-1 antikoerper, LGAS1 antikoerper, LGALS1 antikoerper, MGC64502 antikoerper, GB10026 antikoerper, AA410090 antikoerper, Gal-1 antikoerper, Galbp antikoerper, L-14.5 antikoerper, L14 antikoerper, Lect14 antikoerper, galectin-1 antikoerper, Galaptin antikoerper, galectin 1 antikoerper, galectin-1 antikoerper, lectin, galactoside-binding, soluble, 1 L homeolog antikoerper, protein enabled antikoerper, lectin, galactose binding, soluble 1 antikoerper, LGALS1 antikoerper, Lgals1 antikoerper, CC1G_05003 antikoerper, CC1G_05004 antikoerper, lgals1.L antikoerper, LOC408848 antikoerper
- Molekulargewicht
- 14 kDa
- Gen-ID
- 3956, 445351
- UniProt
- P09382
- Pathways
- Carbohydrate Homeostasis
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