TRIP12 Antikörper (AA 1-240)
Kurzübersicht für TRIP12 Antikörper (AA 1-240) (ABIN6149543)
Target
Alle TRIP12 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-240
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Sequenz
- MSNRPNNNPG GSLRRSQRNT AGAQPQDDSI GGRSHLGQAK HKGYSPPESR KSNSKAPKVQ SNTTSELSRG HLSKRSCSSS SAVIVPQPED PDRANTSERQ KTGQVPKKDN SRGVKRSASP DYNRTNSPSS AKKPKALQHT ESPSETNKPH SKSKKRHLDQ EQQLKSAQSP STSKAHTRKS GATGGSRSQK RKRTESSCVK SGSGSESTGA EERSAKPTKL ASKSATSAKA GCSTITDSSS
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human TRIP12 (NP_001271143.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- TRIP12 (Thyroid Hormone Receptor Interactor 12 (TRIP12))
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Andere Bezeichnung
- TRIP12
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Hintergrund
- The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.,TRIP12,TRIP-12,ULF,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,TRIP12
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Molekulargewicht
- 192 kDa/220 kDa/223 kDa/225 kDa
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Gen-ID
- 9320
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UniProt
- Q14669
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Pathways
- Nuclear Hormone Receptor Binding
Target
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