TRIP10 Antikörper (AA 246-545)

Produktnummer ABIN6149541

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRIP10 in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TRIP10 Antikörper (AA 246-545) (ABIN6149541)

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-TRIP10 Antikörper

Bindungsspezifität: AA 246-545

Sequenz: AKCLEGMKVA ANAVDPKNDS HVLIELHKSG FARPGDVEFE DFSQPMNRAP SDSSLGTPSD GRPELRGPGR SRTKRWPFGK KNKTVVTEDF SHLPPEQQRK RLQQQLEERS RELQKEVDQR EALKKMKDVY EKTPQMGDPA SLEPQIAETL SNIERLKLEV QKYEAWLAEA ESRVLSNRGD SLSRHARPPD PPASAPPDSS SNSASQDTKE SSEEPPSEES QDTPIYTEFD EDFEEEPTSP IGHCVAIYHF EGSSEGTISM AEGEDLSLME EDKGDGWTRV RRKEGGEGYV PTSYLRVTLN

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 246-545 of human TRIP10 (NP_004231.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TRIP10

Target: TRIP10 (Thyroid Hormone Receptor Interactor 10 (TRIP10))

Andere Bezeichnung: TRIP10

Hintergrund: Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.,TRIP10,CIP4,HSTP,STOT,STP,TRIP-10,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,G protein signaling,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,Cytoskeleton,Microfilaments,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,TRIP10

Molekulargewicht: 39 kDa/52 kDa/62 kDa/67 kDa/68 kDa

Gen-ID: 9322

UniProt: Q15642