Tescalcin Antikörper (AA 135-214)
Kurzübersicht für Tescalcin Antikörper (AA 135-214) (ABIN6149009)
Target
Alle Tescalcin (TESC) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 135-214
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Sequenz
- YRNVVEELLS GNPHIEKESA RSIADGAMME AASVCMGQME PDQVYEGITF EDFLKIWQGI DIETKMHVRF LNMETMALCH
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 135-214 of human TESC (NP_060369.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Tescalcin (TESC)
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Andere Bezeichnung
- TESC
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Hintergrund
- Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+/H(+ exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward megakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin.,TESC,CHP3,TSC,tescalcin,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Neuroscience,Calcium Signaling,TESC
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Molekulargewicht
- 18 kDa/21 kDa/24 kDa
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Gen-ID
- 54997
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UniProt
- Q96BS2
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Pathways
- Proton Transport
Target
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