TBC1D23 Antikörper (AA 250-600)

Produktnummer ABIN6148882

Der Kaninchen Polyklonal Anti-TBC1D23-Antikörper wurde für WB validiert. Er ist geeignet, TBC1D23 in Proben von Human zu detektieren.

Kurzübersicht für TBC1D23 Antikörper (AA 250-600) (ABIN6148882)

Target: TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBC1D23 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TBC1D23 Antikörper

Bindungsspezifität: AA 250-600

Sequenz: SDSKEEVIKF LENTPSSLNI EDIEDLFSLA QYYCSKTPAS FRKDNHHLFG STLLGIKDDD ADLSQALCLA ISVSEILQAN QLQGEGVRFF VVDCRPAEQY NAGHLSTAFH LDSDLMLQNP SEFAQSVKSL LEAQKQSIES GSIAGGEHLC FMGSGREEED MYMNMVLAHF LQKNKEYVSI ASGGFMALQQ HLADINVDGP ENGYGHWIAS TSGSRSSINS VDGESPNGSS DRGMKSLVNK MTVALKTKSV NVREKVISFI ENTSTPVDRM SFNLPWPDRS CTERHVSSSD RVGKPYRGVK PVFSIGDEEE YDTDEIDSSS MSDDDRKEVV NIQTWINKPD VKHHFPCKEV K

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-600 of human TBC1D23 (NP_001186127.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TBC1D23

Target: TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))

Andere Bezeichnung: TBC1D23

Hintergrund: Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning (By similarity. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS challenge (By similarity.,TBC1D23,NS4ATP1,TBC1D23

Molekulargewicht: 76 kDa/78 kDa

Gen-ID: 55773

UniProt: Q9NUY8