TAPBP Antikörper (AA 30-260)
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- Target Alle TAPBP Antikörper anzeigen
- TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
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Bindungsspezifität
- AA 30-260
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TAPBP Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequenz
- VEDASGKGLA KRPGALLLRQ GPGEPPPRPD LDPELYLSVH DPAGALQAAF RRYPRGAPAP HCEMSRFVPL PASAKWASGL TPAQNCPRAL DGAWLMVSIS SPVLSLSSLL RPQPEPQQEP VLITMATVVL TVLTHTPAPR VRLGQDALLD LSFAYMPPTS EAASSLAPGP PPFGLEWRRQ HLGKGHLLLA ATPGLNGQMP AAQEGAVAFA AWDDDEPWGP WTGNGTFWLP T
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-260 of human TAPBP (NP_757345.2).
- Isotyp
- IgG
- Top Product
- Discover our top product TAPBP Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TAPBP (TAP Binding Protein (Tapasin) (TAPBP))
- Andere Bezeichnung
- TAPBP (TAPBP Produkte)
- Hintergrund
- This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.,TAPBP,NGS17,TAPA,TPN,TPSN,tapasin,Signal Transduction,Immunology & Inflammation,TAPBP
- Molekulargewicht
- 38 kDa/43 kDa/47 kDa/53 kDa
- Gen-ID
- 6892
- UniProt
- O15533
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