TAPBP Antikörper (AA 30-260)

Produktnummer ABIN6148848

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TAPBP in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TAPBP Antikörper (AA 30-260) (ABIN6148848)

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAPBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TAPBP Antikörper

Bindungsspezifität: AA 30-260

Sequenz: VEDASGKGLA KRPGALLLRQ GPGEPPPRPD LDPELYLSVH DPAGALQAAF RRYPRGAPAP HCEMSRFVPL PASAKWASGL TPAQNCPRAL DGAWLMVSIS SPVLSLSSLL RPQPEPQQEP VLITMATVVL TVLTHTPAPR VRLGQDALLD LSFAYMPPTS EAASSLAPGP PPFGLEWRRQ HLGKGHLLLA ATPGLNGQMP AAQEGAVAFA AWDDDEPWGP WTGNGTFWLP T

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-260 of human TAPBP (NP_757345.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TAPBP

Target: TAPBP (TAP Binding Protein (Tapasin) (TAPBP))

Andere Bezeichnung: TAPBP

Hintergrund: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.,TAPBP,NGS17,TAPA,TPN,TPSN,tapasin,Signal Transduction,Immunology & Inflammation,TAPBP

Molekulargewicht: 38 kDa/43 kDa/47 kDa/53 kDa

Gen-ID: 6892

UniProt: O15533