APOH Antikörper
Kurzübersicht für APOH Antikörper (ABIN614872)
Target
Alle APOH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody recognizes beta2GP-I. A single precipitin arc is observed with normal plasma. No arc was seen with beta2GP-I deficient plasma.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, porcine, rat, rabbit, canine
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Aufreinigung
- Immunoaffinity chromatography
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Immunogen
- Human beta2-Glycoprotein-I (beta2GP-I) purified from plasma Genename: APOH
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 2.0 mg/mL
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Buffer
- 10 mM HEPES, pH 7.4, 0.15 M sodium chloride, 50 % glycerol
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- APOH (Apolipoprotein H (Beta-2-Glycoprotein I) (APOH))
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Andere Bezeichnung
- Apolipoprotein H (Apo H)
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Hintergrund
- Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.Synonyms: APC Inhibitor, Anticardiolipin Cofactor, Apo-H, ApoH, B2G1, B2GPI, Beta-2-glycoprotein I, Beta2GPI
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Gen-ID
- 350
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NCBI Accession
- NP_000033
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UniProt
- P02749
Target
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