SULF1 Antikörper (AA 400-700)
Kurzübersicht für SULF1 Antikörper (AA 400-700) (ABIN6148697)
Target
Alle SULF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 400-700
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Sequenz
- TNKKAKIWRD TFLVERGKFL RKKEESSKNI QQSNHLPKYE RVKELCQQAR YQTACEQPGQ KWQCIEDTSG KLRIHKCKGP SDLLTVRQST RNLYARGFHD KDKECSCRES GYRASRSQRK SQRQFLRNQG TPKYKPRFVH TRQTRSLSVE FEGEIYDINL EEEEELQVLQ PRNIAKRHDE GHKGPRDLQA SSGGNRGRML ADSSNAVGPP TTVRVTHKCF ILPNDSIHCE RELYQSARAW KDHKAYIDKE IEALQDKIKN LREVRGHLKR RKPEECSCSK QSYYNKEKGV KKQEKLKSHL H
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Kreuzreaktivität
- Human, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 400-700 of human SULF1 (NP_055985.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SULF1 (Sulfatase 1 (SULF1))
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Andere Bezeichnung
- SULF1
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Hintergrund
- This gene encodes an extracellular heparan sulfate endosulfatase. The encoded enzyme selectively removes 6-O-sulfate groups from heparan sulfate chains of heparan sulfate proteoglycans (HSPGs). The enzyme is secreted through the Golgi and is subsequently localized to the cell surface. The expression of this gene may be down-regulated in several types of cancer, including hepatocellular (HCC), ovarian and breast cancers. Alternative splicing results in multiple transcript variants.,SULF1,SULF-1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,SULF1
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Molekulargewicht
- 101 kDa
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Gen-ID
- 23213
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UniProt
- Q8IWU6
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Pathways
- EGFR Signaling Pathway
Target
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