Stabilin 2 (STAB2) (AA 1550-1850) Antikörper

Produktnummer ABIN6148547

Der Kaninchen Polyklonal Anti--Antikörper wurde für WB validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für Stabilin 2 (STAB2) (AA 1550-1850) Antikörper (ABIN6148547)

Target: Stabilin 2 (STAB2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 1550-1850

Sequenz: GKVCTLINVC LTKNGGCSEF AICNHTGQVE RTCTCKPNYI GDGFTCRGSI YQELPKNPKT SQYFFQLQEH FVKDLVGPGP FTVFAPLSAA FDEEARVKDW DKYGLMPQVL RYHVVACHQL LLENLKLISN ATSLQGEPIV ISVSQSTVYI NNKAKIISSD IISTNGIVHI IDKLLSPKNL LITPKDNSGR ILQNLTTLAT NNGYIKFSNL IQDSGLLSVI TDPIHTPVTL FWPTDQALHA LPAEQQDFLF NQDNKDKLKE YLKFHVIRDA KVLAVDLPTS TAWKTLQGSE LSVKCGAGRD I

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1550-1850 of human STAB2 (NP_060034.9).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Antigendetails

Target: Stabilin 2 (STAB2)

Andere Bezeichnung: STAB2

Hintergrund: This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.,STAB2,FEEL2,FELE-2,FELL2,FEX2,HARE,SCARH1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,STAB2

Molekulargewicht: 276 kDa

Gen-ID: 55576

UniProt: Q8WWQ8

Pathways: Glycosaminoglycan Metabolic Process