SOX30 Antikörper (AA 1-150)

Produktnummer ABIN6148300

Produktdetails anti-SOX30 Antikörper

Target: SOX30 (SRY (Sex Determining Region Y)-Box 30 (SOX30))

Bindungsspezifität: AA 1-150

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX30 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MERARPEPPP PPPPPPRQPP RPTPPRPLRP APPAQPVEAA TFRAAAAERS QSPSAQATAA MAAVASSCGE AAAAGAQAAG TRRLLQVKPE QVLLLPPGGP GVPPAPDEGA AAAAAAAAAA ASSAQARLLQ LRPELLLLPP QSAADGGPCR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of mouse SOX30 (NP_775560.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-SOX30 Antikörper (ABIN6148300)

Chen, Zheng, Gao, Lin, Yang, Wang, Wang, Xie, Hua, Liu, Sha, Griswold, Li, Tang, Tong: "Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis." in: Cell research, Vol. 28, Issue 9, pp. 879-896, (2018) (PubMed).

Bai, Fu, Yin, Cui, Yue, Li, Cheng, Tan, Liu, Guo, Zhang, Xie, He, Wang, Feng, Xin, Zhang, Lin, Shen, Sun, Guo, Zheng, Ye: "Sox30 initiates transcription of haploid genes during late meiosis and spermiogenesis in mouse testes." in: Development (Cambridge, England), Vol. 145, Issue 13, (2018) (PubMed).

Details zu SOX30

Target: SOX30 (SRY (Sex Determining Region Y)-Box 30 (SOX30))

Andere Bezeichnung: SOX30 (SOX30 Produkte)

Hintergrund: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein acts as a transcriptional regulator when present in a complex with other proteins. It can activate p53 transcription to promote tumor cell apoptosis in lung cancer. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 5.,SOX30,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Stem Cells,Germline Stem Cells,SOX30

Molekulargewicht: 83 kDa

Gen-ID: 214105

UniProt: Q8CGW4