Sortilin 1 Antikörper (AA 520-760)

Produktnummer ABIN6148281

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Sortilin 1 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Sortilin 1 Antikörper (AA 520-760) (ABIN6148281)

Target: Sortilin 1 (SORT1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sortilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Sortilin 1 Antikörper

Bindungsspezifität: AA 520-760

Sequenz: EGPHYYTILD SGGIIVAIEH SSRPINVIKF STDEGQCWQT YTFTRDPIYF TGLASEPGAR SMNISIWGFT ESFLTSQWVS YTIDFKDILE RNCEEKDYTI WLAHSTDPED YEDGCILGYK EQFLRLRKSS VCQNGRDYVV TKQPSICLCS LEDFLCDFGY YRPENDSKCV EQPELKGHDL EFCLYGREEH LTTNGYRKIP GDKCQGGVNP VREVKDLKKK CTSNFLSPEK QNSKSNSVPI I

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 520-760 of human SORT1 (NP_002950.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Sortilin 1

Target: Sortilin 1 (SORT1)

Andere Bezeichnung: SORT1

Hintergrund: This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants.,SORT1,Gp95,LDLCQ6,NT3,NTR3,sortilin,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Heart,Lipids,Lipoproteins/Apolipoproteins,Cardiovascular diseases,Heart disease,SORT1

Molekulargewicht: 77 kDa/92 kDa

Gen-ID: 6272

UniProt: Q99523

Pathways: Neurotrophin Signalübertragung