SNX13 Antikörper (AA 50-230)
Kurzübersicht für SNX13 Antikörper (AA 50-230) (ABIN6148236)
Target
Alle SNX13 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 50-230
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Sequenz
- FGKTNSEKYL EQCEHSFLPP TSPGVPKCLE EMKREARTIK IDRRLTGANI IDEPLQQVIQ FSLRDYVQYW YYTLSDDESF LLEIRQTLQN ALIQFATRSK EIDWQPYFTT RIVDDFGTHL RVFRKAQQKI TEKDDQVKGT AEDLVDTFFE VEVEMEKEVC RDLVCTSPKD EEGFLRDLCE V
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 50-230 of human SNX13 (NP_055947.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SNX13 (Sorting Nexin 13 (SNX13))
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Andere Bezeichnung
- SNX13
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Hintergrund
- This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.,SNX13,RGS-PX1,Signal Transduction,G protein signaling,SNX13
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Molekulargewicht
- 110 kDa/112 kDa
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Gen-ID
- 23161
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UniProt
- Q9Y5W8
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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