SNAIL Antikörper (AA 1-264)

Produktnummer ABIN6148175

Der Kaninchen Polyklonal Anti-SNAIL-Antikörper wurde für WB und IHC validiert. Er ist geeignet, SNAIL in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für SNAIL Antikörper (AA 1-264) (ABIN6148175)

Target: SNAIL (SNAI1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SNAIL Antikörper

Bindungsspezifität: AA 1-264

Sequenz: MPRSFLVRKP SDPNRKPNYS ELQDSNPEFT FQQPYDQAHL LAAIPPPEIL NPTASLPMLI WDSVLAPQAQ PIAWASLRLQ ESPRVAELTS LSDEDSGKGS QPPSPPSPAP SSFSSTSVSS LEAEAYAAFP GLGQVPKQLA QLSEAKDLQA RKAFNCKYCN KEYLSLGALK MHIRSHTLPC VCGTCGKAFS RPWLLQGHVR THTGEKPFSC PHCSRAFADR SNLRAHLQTH SDVKKYQCQA CARTFSRMSL LHKHQESGCS GCPR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human Snail (NP_005976.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-SNAIL Antikörper (ABIN6148175)

Mei, Xiang, Cong, Zhang, Li, Yi, Park, Han, Wu, Yu: "Claudin-3 is required for modulation of paracellular permeability by TNF-α through ERK1/2/slug signaling axis in submandibular gland." in: Cellular signalling, Vol. 27, Issue 10, pp. 1915-27, (2016) (PubMed).

Wang, Li, Chen, Tan, Sun, Xia, Li, Yu, Gong, Tang, Ji, Yuan, Shanglong Yao, Shang: "Maresin 1 Inhibits Epithelial-to-Mesenchymal Transition in Vitro and Attenuates Bleomycin Induced Lung Fibrosis in Vivo." in: Shock (Augusta, Ga.), Vol. 44, Issue 5, pp. 496-502, (2016) (PubMed).

Details zu SNAIL

Target: SNAIL (SNAI1)

Andere Bezeichnung: SNAI1

Hintergrund: The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.,SNAI1,SLUGH2,SNA,SNAH,SNAIL,SNAIL1,dJ710H13.1,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Cardiovascular,Heart,Cardiogenesis,SNAI1

Molekulargewicht: 29 kDa

Gen-ID: 6615

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling