SMYD5 Antikörper

Produktnummer ABIN6148173

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMYD5 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SMYD5 Antikörper (ABIN6148173)

Target: SMYD5 (SMYD Family Member 5 (SMYD5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMYD5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SMYD5 Antikörper

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant protein of human SMYD5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SMYD5

Target: SMYD5 (SMYD Family Member 5 (SMYD5))

Andere Bezeichnung: SMYD5

Hintergrund: Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4 to form trimethylated histone H4 lysine 20 (H4K20me3 which represents a specific tag for epigenetic transcriptional repression (By similarity. In association with the NCoR corepressor complex, is involved in the repression of toll-like receptor 4 (TLR4-target inflammatory genes in macrophages by catalyzing the formation of H4K20me3 at the gene promoters (By similarity. Plays an important role in embryonic stem (ES cell self-renewal and differentiation (By similarity. Promotes ES cell maintenance by silencing differentiation genes through deposition of H4K20me3 marks (By similarity. Maintains genome stability of ES cells during differentiation through regulation of heterochromatin formation and repression of endogenous repetitive DNA elements by depositing H4K20me3 marks.,SMYD5,NN8-4AG,RAI15,RRG1,ZMYND23,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,SMYD5

Molekulargewicht: 47 kDa

Gen-ID: 10322

UniProt: Q6GMV2