Ubinuclein 1 Antikörper (N-Term)

Produktnummer ABIN614815

Dieser Maus Monoklonal Antikörper detektiert spezifisch Ubinuclein 1 in WB und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Ubinuclein 1 Antikörper (N-Term) (ABIN614815)

Target: Ubinuclein 1 (UBN1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ubinuclein 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Klon: UBN1-02

Produktdetails anti-Ubinuclein 1 Antikörper

Bindungsspezifität: AA 1-190, N-Term

Spezifität: This antibody recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Protein-A affinity chromatography

Reinheit: > 95 % pure by SDS-PAGE

Immunogen: Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu Ubinuclein 1

Target: Ubinuclein 1 (UBN1)

Andere Bezeichnung: Ubinuclein-1 (UBN1)

Hintergrund: Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.Synonyms: HIRA-binding protein, Protein VT4, Ubiquitously expressed nuclear protein

Gen-ID: 29855

NCBI Accession: NP_058632

UniProt: Q9NPG3