CD81 Antikörper

Produktnummer ABIN614802

Dieses Anti-CD81-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD81 in FACS, WB, IP, IF, Func und IHC (p). Geeignet für Human, Kaninchen und Cat. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für CD81 Antikörper (ABIN614802)

Target: CD81

Reaktivität: Human, Kaninchen, Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD81 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: M38

Produktdetails anti-CD81 Antikörper

Spezifität: This antibody reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Feline (Cat), Rabbit

Aufreinigung: Protein-A affinity chromatography

Reinheit: > 95 % pure by SDS-PAGE

Immunogen: MOLT-4 (human T-ALL cell line)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-CD81 Antikörper (ABIN614802)

Escola, Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81 / TAPA1

Hintergrund: CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells - e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.Synonyms: 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1

Gen-ID: 975

NCBI Accession: NP_004347

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C