SIRT6 Antikörper (C-Term)
Kurzübersicht für SIRT6 Antikörper (C-Term) (ABIN6147800)
Target
Alle SIRT6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- NLQPTKHDRQ ADLRIHGYVD EVMCRLMKHL GLEIPAWDGP CVLDKALPPL PRPVALKAEP PVHLNGAVHV SYKSKPNSPI LHRPPKRVKT EAAPS
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of mouse SIRT6 (NP_001156902.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer." in: The Journal of international medical research, Vol. 46, Issue 4, pp. 1517-1527, (2018) (PubMed).
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: "Downregulation of SIRT6 is associated with poor prognosis in patients with non-small cell lung cancer." in: The Journal of international medical research, Vol. 46, Issue 4, pp. 1517-1527, (2018) (PubMed).
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- SIRT6 (Sirtuin 6 (SIRT6))
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Andere Bezeichnung
- SIRT6
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Hintergrund
- This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.,SIRT6,SIR2L6,sirtuin 6,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Deacetylation,SIRT6
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Molekulargewicht
- 36 kDa/39 kDa
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Gen-ID
- 50721
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UniProt
- Q8N6T7
Target
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