SIRT3 Antikörper (C-Term)

Produktnummer ABIN6147792

Der Kaninchen Polyklonal Anti-SIRT3-Antikörper wurde für WB, IHC und IP validiert. Er ist geeignet, SIRT3 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für SIRT3 Antikörper (C-Term) (ABIN6147792)

Target: SIRT3 (Sirtuin 3 (SIRT3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-SIRT3 Antikörper

Bindungsspezifität: C-Term

Sequenz: QRFLLHVVDF PMADLLLILG TSLEVEPFAS LTEAVRSSVP RLLINRDLVG PLAWHPRSRD VAQLGDVVHG VESLVELLGW TEEMRDLVQR ETGKLDGPDK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human SIRT3 (NP_036371.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:500

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-SIRT3 Antikörper (ABIN6147792)

Xu, Gao, Zhang, Wei, Chen, Dai, Zeng, Zhao: "SIRT1/3 Activation by Resveratrol Attenuates Acute Kidney Injury in a Septic Rat Model." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 7296092, (2017) (PubMed).

Details zu SIRT3

Target: SIRT3 (Sirtuin 3 (SIRT3))

Andere Bezeichnung: SIRT3

Hintergrund: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.,SIRT3,SIR2L3,sirtuin 3,Epigenetics & Nuclear Signaling,SIRT3

Molekulargewicht: 28 kDa/43 kDa

Gen-ID: 23410

UniProt: Q9NTG7