SIPA1 Antikörper (AA 763-1042)
Kurzübersicht für SIPA1 Antikörper (AA 763-1042) (ABIN6147778)
Target
Alle SIPA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 763-1042
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Sequenz
- ESGRPRRSFS ELYTLSLQEP SRRGAPDPVQ DEVQGVTLLP TTKQLLHLCL QDGGSPPGPG DLAEERTEFL HSQNSLSPRS SLSDEAPVLP NTTPDLLLAT TAKPSVPSAD SETPLTQDRP GSPSGSEDKG NPAPELRASF LPRTLSLRNS ISRIMSEAGS GTLEDEWQAI SEIASTCNTI LESLSREGQP IPESGDPKGT PKSDAEPEPG NLSEKVSHLE SMLRKLQEDL QKEKADRAAL EEEVRSLRHN NRRLQAESES AATRLLLASK QLGSPTADLA
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 763-1042 of human SIPA1 (NP_694985.29).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:100 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SIPA1 (Signal-Induced Proliferation-Associated 1 (SIPA1))
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Andere Bezeichnung
- SIPA1
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Hintergrund
- The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date.,SIPA1,SPA1,Epigenetics & Nuclear Signaling,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,Stem Cells,Embryonic Stem Cells,SIPA1
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Molekulargewicht
- 112 kDa
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Gen-ID
- 6494
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UniProt
- Q96FS4
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Pathways
- Response to Water Deprivation
Target
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